Patient Care: IGF1-Hormone LR3

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Image Credits: Google.com 

“Three things in life – your health, your mission, and the people you love. That’s it. “ - Naval Ravikant

What is IGF1- LR3 Growth Hormone? 

As medical innovations advance, there are a series of important inclusions in patient care, which make the applications of minimally invasive processes that much more effective. Welcome to our patient care series. Periodically, we will introduce you to some aspects of your orthopaedic care, that will educate you on the latest and greatest in medical innovation. When it comes to orthopaedic care, the acute cases are normally treated with over the counter treatments or minimally invasive procedures that will enable you to be able to be in and out of the practice within a few hours. 

For more complicated healing procedures, orthopaedic surgeons have introduced some synthetic help, so that the body can help to heal itself. Theoretically, it was identified that certain aspects of the human body are slow healing, and if damaged, will often require some transplants to restore the area. With detailed investigation of healing mechanisms, root causes of healing have been identified, synthesized and subsequently injected into the body as catalysts for the healing process. With much success, protein therapies such as the IGF1 Hormone LR3 have successfully be implemented into medical therapies. 

While many of these therapies are new additions to existing therapies, and may not necessarily be covered by current insurance packages, independent studies have proven that they are indeed effective. Speak to your orthopaedic surgeon if you feel that you’d love to include new innovations into your therapeutic healing processes. Minimally invasive processes that can facilitate your body’s own natural healing may be just what you are seeking for your current orthopaedic condition. 

The IGF1-LR3 is one element of the Insulin-like Growth Factor hormones which are injected into the body for healing enhancement. As an insulin analogue, the peptide has applications in facilitating bone growth, muscle growth and muscle repair. The scientific name for the IGF-LRS is Long arginine 3-IGF-1. The substituted protein chain of arginine is what differentiates this element from other insulin analogues.

IGF1-LR3 as a protein, stimulates the proliferation and survival of cells. For conditions such as diabetes, all the critical elements for growth are therefore enhanced. This includes the growth of muscle, bone and cartilage. The functions of the protein include: 

  1. A higher bioactivity than insulin promoting growth and healing functions in the injected patient. 

  2. Based on the bioengineering of the peptide, IGF1-LR3 has a higher half life than insulin and natural proteins. As a more stable molecule, it is finding increased applications in the medical industry for culturing and research. 

With a myriad of research proteins available on the market, such as: Melanotan II, CJC-1295, Sermorelin, IGF1-LR3 and GHRP-2, determining the application for research or medical purposes can be a challenge. Talk to your orthopaedic surgeon to determine if the healing attributes of this protein can enhance your healing. If you’re a candidate for treatments such as distraction arthroplasty, your joint restoration could be enhanced by the injection of a protein such as IGF1-LR3. 

Alternate Therapies to IGF1-LR3

How does Stem Cell Therapy Heal My Arthritis?

With the advent of ortho-biologics, arthritis treatments with the facilitation of cartilage restoration is now a modern-day possibility. With options ranging from total joint replacement, to distraction arthroplasty, stem cell therapy and growth factors there are a myriad of evolving technologies and minimally invasive methods that can heal the arthritic site.

As a word of caution, many new therapies are not covered by insurance due to their recency, and the fact that the methods are still being approved by various medical bodies globally. In Australia, growth factors are rebated, whereas stem cell therapy is not. Talk to your orthopedic surgeon about this procedure, and find out how the treatments can be financed. Your doctor may have their own payment options so investigate with them how your therapy can be financed. 

How do Stem Cells or Growth Factors Regenerate the Body? 

The stem cell has long been identified as the regenerative life force in our bodies. With their ability to divide and duplicate, as well as generate new and different stem cells that are relevant to a healing site, it is possible to regenerate cartilage cells and even bone cells. This is great news for the arthritic foot. Over time, the joint can wear away, and with the ability to rebuild it naturally, it will save the individual time from having to go through processes like harvesting. 

How are Stem Cells Administered? 

Stem cells are administered either surgically, or via injection into the arthritic joint. Much like the image above, your orthopaedic surgeon will utilize medical imaging in order to identify where on the body, the stem cells are to be administered. Depending on the severity of the injury, either of the two options will be applied. When the stem cells are being administered, your orthopaedic surgeon will more than likely utilize mesenchymal stem cells that have been harvested from the individual's body. 

When To Approach Your Doctor for Stem Cell Therapy

As a patient, it is very useful to be proactive. Many times, doctors will offer you therapies that are standard practice. If you feel that you want to try something new, you can personally push the envelope and ask them about these next generation therapies. As a transition from external treatments, to natural self healing methods, you may save yourself many months and years of pain. As the field embraces this evolving technology, it will be a joint decision between yourself and your doctor that determines how the therapy is progressed. 

References: 

  1. IGF Hormone LR3: https://www.peprotech.com/en/recombinant-human-igf-i-lr3

  2. IGF Hormone LR3: https://en.wikipedia.org/wiki/IGF-1_LR3

  3. IGF1 and IGF3 Comparison: https://www.bioprocessonline.com/doc/igf-long-igf-lr-is-there-difference-us-peptides-discusses-0001

Reference Articles for Stem Cell Therapy: 

1)Cartilage Restoration: http://www.cartilagerestoration.org/stem-cell-ortho-biologics-and-regenerative-medicine-program

2)Stem Cell Therapy for Arthritis: https://www.arthritis-health.com/treatment/injections/stem-cell-therapy-arthritis

3)Regenerative Stem Cell Therapy for Foot and Ankle Pain: https://www.stemcellctr.com/procedures/foot-ankle/


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